Sex Impacts Microaxial Pump Outcomes in Shock 02/19/26

Cardiology Today
Cardiology Today
Sex Impacts Microaxial Pump Outcomes in Shock 02/19/26
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Welcome to Cardiology Today – Recorded February 19, 2026. This episode summarizes 5 key cardiology studies on topics like interventricular septum and right bundle branch block. Key takeaway: Sex Impacts Microaxial Pump Outcomes in Shock.

Article Links:

Article 1: Sex-Specific Microaxial Flow Pump Use and Outcomes in Infarct-Related Cardiogenic Shock in the DanGer Shock Trial. (Journal of the American College of Cardiology)

Article 2: Post-certification competencies and cardiovascular care delivery. (European heart journal)

Article 3: Conduction disturbances after transcatheter aortic valve implantation. (European heart journal)

Article 4: Delirium in cardiovascular medicine. (European heart journal)

Article 5: Great debate: drug-coated balloons are preferable to drug-eluting stents for coronary in-stent restenosis. (European heart journal)

Full episode page: https://podcast.explainheart.com/podcast/sex-impacts-microaxial-pump-outcomes-in-shock-02-19-26/

📚 Featured Articles

Article 1: Sex-Specific Microaxial Flow Pump Use and Outcomes in Infarct-Related Cardiogenic Shock in the DanGer Shock Trial.

Journal: Journal of the American College of Cardiology

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41222528

Summary: The DanGer Shock trial found that microaxial flow pump use improved outcomes in selected patients with S. T. elevation myocardial infarction and cardiogenic shock. However, the beneficial effect of the microaxial flow pump was observed to be less evident in women compared with men. This secondary analysis determined significant sex differences in baseline characteristics, in-hospital course, and the effectiveness of the microaxial flow pump in S. T. elevation myocardial infarction with cardiogenic shock. This highlights a critical disparity in treatment efficacy based on patient sex.

Article 2: Post-certification competencies and cardiovascular care delivery.

Journal: European heart journal

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41712366

Summary: This analysis emphasizes that while cardiologists achieve core cardiovascular competencies, ongoing training, assessment, and maintenance of post-certification competencies are crucial for effective practice. It shows cardiologists must function as part of a comprehensive multidisciplinary Heart Team across the full spectrum of cardiovascular care. This continuous professional development ensures optimal patient outcomes in the dynamic field of cardiology. These findings reinforce the necessity of lifelong learning beyond initial certification.

Article 3: Conduction disturbances after transcatheter aortic valve implantation.

Journal: European heart journal

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41712363

Summary: Conduction disturbances and permanent pacemaker implantation are among the most common complications observed after transcatheter aortic valve implantation. Studies show that the strongest predictors of these conduction abnormalities include pre-existing right bundle branch block, a short membranous interventricular septum, deep transcatheter heart valve implantation, and the specific transcatheter heart valve type. These findings highlight critical patient and procedural characteristics that significantly influence post-procedural electrical outcomes.

Article 4: Delirium in cardiovascular medicine.

Journal: European heart journal

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41711546

Summary: Delirium is a common neuropsychiatric syndrome frequently observed in cardiovascular medicine, which studies show is associated with prolonged hospitalization, increased mortality, and long-term cognitive decline. Patients undergoing interventional or surgical cardiovascular procedures, such as transcatheter aortic valve replacement, surgical aortic valve replacement, coronary artery bypass grafting, or percutaneous coronary interventions, are particularly vulnerable to its development. These findings underscore the significant impact of delirium on patient outcomes and identify high-risk populations.

Article 5: Great debate: drug-coated balloons are preferable to drug-eluting stents for coronary in-stent restenosis.

Journal: European heart journal

PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41711522

Summary: Drug-coated balloons have demonstrated efficacy as an alternative to drug-eluting stents in percutaneous coronary interventions, particularly favored for their “leave nothing behind” approach. Recent clinical evidence supports the effectiveness of drug-coated balloons in treating both small vessel disease and bifurcation lesions. This indicates that drug-coated balloons provide a significant therapeutic option for specific coronary artery disease subsets.

📝 Transcript

Today’s date is February 19, 2026. Welcome to Cardiology Today. Here are the latest research findings.

Article number one. Sex-Specific Microaxial Flow Pump Use and Outcomes in Infarct-Related Cardiogenic Shock in the DanGer Shock Trial. The DanGer Shock trial found that microaxial flow pump use improved outcomes in selected patients with S. T. elevation myocardial infarction and cardiogenic shock. However, the beneficial effect of the microaxial flow pump was observed to be less evident in women compared with men. This secondary analysis determined significant sex differences in baseline characteristics, in-hospital course, and the effectiveness of the microaxial flow pump in S. T. elevation myocardial infarction with cardiogenic shock. This highlights a critical disparity in treatment efficacy based on patient sex.

Article number two. Post-certification competencies and cardiovascular care delivery. This analysis emphasizes that while cardiologists achieve core cardiovascular competencies, ongoing training, assessment, and maintenance of post-certification competencies are crucial for effective practice. It shows cardiologists must function as part of a comprehensive multidisciplinary Heart Team across the full spectrum of cardiovascular care. This continuous professional development ensures optimal patient outcomes in the dynamic field of cardiology. These findings reinforce the necessity of lifelong learning beyond initial certification.

Article number three. Conduction disturbances after transcatheter aortic valve implantation. Conduction disturbances and permanent pacemaker implantation are among the most common complications observed after transcatheter aortic valve implantation. Studies show that the strongest predictors of these conduction abnormalities include pre-existing right bundle branch block, a short membranous interventricular septum, deep transcatheter heart valve implantation, and the specific transcatheter heart valve type. These findings highlight critical patient and procedural characteristics that significantly influence post-procedural electrical outcomes.

Article number four. Delirium in cardiovascular medicine. Delirium is a common neuropsychiatric syndrome frequently observed in cardiovascular medicine, which studies show is associated with prolonged hospitalization, increased mortality, and long-term cognitive decline. Patients undergoing interventional or surgical cardiovascular procedures, such as transcatheter aortic valve replacement, surgical aortic valve replacement, coronary artery bypass grafting, or percutaneous coronary interventions, are particularly vulnerable to its development. These findings underscore the significant impact of delirium on patient outcomes and identify high-risk populations.

Article number five. Great debate: drug-coated balloons are preferable to drug-eluting stents for coronary in-stent restenosis. Drug-coated balloons have demonstrated efficacy as an alternative to drug-eluting stents in percutaneous coronary interventions, particularly favored for their “leave nothing behind” approach. Recent clinical evidence supports the effectiveness of drug-coated balloons in treating both small vessel disease and bifurcation lesions. This indicates that drug-coated balloons provide a significant therapeutic option for specific coronary artery disease subsets.

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🔍 Keywords

interventricular septum, right bundle branch block, small vessel disease, cardiovascular care, multidisciplinary approach, cardiologist competencies, drug-coated balloons, conduction disturbances, S. T. elevation myocardial infarction, transcatheter aortic valve replacement, sex differences, cognitive decline, cardiogenic shock, transcatheter aortic valve implantation, drug-eluting stents, post-certification training, cardiovascular medicine, prolonged hospitalization, in-stent restenosis, percutaneous coronary intervention, permanent pacemaker implantation, delirium, microaxial flow pump, Heart Team, DanGer Shock Trial, mortality.

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