Pediatric Kidney Transplant: 69% Rehospitalized within Year. 11/29/25
Welcome to Cardiology Today â Recorded November 29, 2025. This episode summarizes 5 key cardiology studies on topics like Left Ventricular Ejection Fraction and British Columbia. Key takeaway: Pediatric Kidney Transplant: 69% Rehospitalized within Year..
Article Links:
Article 1: Association of rehospitalization after pediatric kidney transplantation with kidney function at 1-year post-transplant and long-term allograft failure. (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
Article 2: Noninvasive Assessment of Right Ventricular-Pulmonary Arterial Coupling in Repaired Tetralogy of Fallot by Magnetic Resonance Imaging. (Journal of the American Heart Association)
Article 3: Left Ventricular Ejection Fraction Response After Atrial Fibrillation Ablation: Clinical Predictors and Development of the PACED Score. (Heart rhythm)
Article 4: Road exposure after cardioverter-defibrillator implantation and its potential influence on reported motor vehicle crash risks. (The American journal of cardiology)
Article 5: Association of Body Mass Index with ten-year outcomes in asymptomatic stage a/B heart failure patients: Insights from the CHART-2 study. (International journal of cardiology)
Full episode page: https://podcast.explainheart.com/podcast/pediatric-kidney-transplant-69-rehospitalized-within-year-11-29-25/
đ Featured Articles
Article 1: Association of rehospitalization after pediatric kidney transplantation with kidney function at 1-year post-transplant and long-term allograft failure.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41314615
Summary: This study found that 29 percent of incident pediatric kidney transplant recipients experienced rehospitalization within the first 30 days post-transplant. Furthermore, over two-thirds of children, specifically 69 percent, were rehospitalized within the first year following their transplant procedure. These findings highlight a high burden of early rehospitalizations in pediatric kidney transplant patients, underscoring the need for improved post-transplant care strategies.
Article 2: Noninvasive Assessment of Right Ventricular-Pulmonary Arterial Coupling in Repaired Tetralogy of Fallot by Magnetic Resonance Imaging.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41294083
Summary: This study evaluated a noninvasive, volume-based parameter for Right Ventricular-Pulmonary Arterial coupling in a cohort of 92 pediatric and 105 adult patients with repaired Tetralogy of Fallot. Right Ventricular-Pulmonary Arterial coupling quantifies right ventricular contractility in relation to its afterload, a crucial measure traditionally requiring high-fidelity catheter-derived pressure-volume loops. The investigation explored this noninvasive parameter’s utility in assessing ventricular function in this patient population, addressing the need for less invasive evaluation methods compared to traditional approaches.
Article 3: Left Ventricular Ejection Fraction Response After Atrial Fibrillation Ablation: Clinical Predictors and Development of the PACED Score.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41314586
Summary: This multicenter cohort study identified pre-procedural predictors of Left Ventricular Ejection Fraction response following atrial fibrillation ablation in patients with Left Ventricular Systolic Dysfunction. The study included patients with atrial fibrillation and a Left Ventricular Ejection Fraction less than 50 percent who underwent an index ablation procedure. The study developed the P. A. C. E. D. Score to pragmatically stratify patients for Left Ventricular Ejection Fraction response after ablation. Catheter ablation for atrial fibrillation improves outcomes in patients with Left Ventricular Systolic Dysfunction, making prediction of Left Ventricular Ejection Fraction response clinically valuable.
Article 4: Road exposure after cardioverter-defibrillator implantation and its potential influence on reported motor vehicle crash risks.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41314365
Summary: This study obtained 18 years of population-based health and driving data from British Columbia, Canada, for drivers who underwent implantable cardioverter-defibrillator implantation. Researchers estimated drivers’ monthly road exposure relative to baseline to understand its influence on motor vehicle crash risk interpretation. This investigation highlights how transient reductions in driving after implantable cardioverter-defibrillator implantation can significantly affect the reported crash risk, necessitating careful consideration in risk assessment.
Article 5: Association of Body Mass Index with ten-year outcomes in asymptomatic stage a/B heart failure patients: Insights from the CHART-2 study.
Journal: International journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41314304
Summary: This study prospectively evaluated 501 asymptomatic stage A heart failure patients and 4767 asymptomatic stage B heart failure patients, with a mean age of 67.6 years, 71.1 percent of whom were male. It examined the association of Body Mass Index with ten-year outcomes in these early stage heart failure patients. The research addressed a gap in understanding the prognostic importance of Body Mass Index in asymptomatic heart failure, a topic where previous studies largely focused on stage C and D heart failure patients.
đ Transcript
Today’s date is November 29, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Association of rehospitalization after pediatric kidney transplantation with kidney function at 1-year post-transplant and long-term allograft failure. This study found that 29 percent of incident pediatric kidney transplant recipients experienced rehospitalization within the first 30 days post-transplant. Furthermore, over two-thirds of children, specifically 69 percent, were rehospitalized within the first year following their transplant procedure. These findings highlight a high burden of early rehospitalizations in pediatric kidney transplant patients, underscoring the need for improved post-transplant care strategies.
Article number two. Noninvasive Assessment of Right Ventricular-Pulmonary Arterial Coupling in Repaired Tetralogy of Fallot by Magnetic Resonance Imaging. This study evaluated a noninvasive, volume-based parameter for Right Ventricular-Pulmonary Arterial coupling in a cohort of 92 pediatric and 105 adult patients with repaired Tetralogy of Fallot. Right Ventricular-Pulmonary Arterial coupling quantifies right ventricular contractility in relation to its afterload, a crucial measure traditionally requiring high-fidelity catheter-derived pressure-volume loops. The investigation explored this noninvasive parameter’s utility in assessing ventricular function in this patient population, addressing the need for less invasive evaluation methods compared to traditional approaches.
Article number three. Left Ventricular Ejection Fraction Response After Atrial Fibrillation Ablation: Clinical Predictors and Development of the PACED Score. This multicenter cohort study identified pre-procedural predictors of Left Ventricular Ejection Fraction response following atrial fibrillation ablation in patients with Left Ventricular Systolic Dysfunction. The study included patients with atrial fibrillation and a Left Ventricular Ejection Fraction less than 50 percent who underwent an index ablation procedure. The study developed the P. A. C. E. D. Score to pragmatically stratify patients for Left Ventricular Ejection Fraction response after ablation. Catheter ablation for atrial fibrillation improves outcomes in patients with Left Ventricular Systolic Dysfunction, making prediction of Left Ventricular Ejection Fraction response clinically valuable.
Article number four. Road exposure after cardioverter-defibrillator implantation and its potential influence on reported motor vehicle crash risks. This study obtained 18 years of population-based health and driving data from British Columbia, Canada, for drivers who underwent implantable cardioverter-defibrillator implantation. Researchers estimated drivers’ monthly road exposure relative to baseline to understand its influence on motor vehicle crash risk interpretation. This investigation highlights how transient reductions in driving after implantable cardioverter-defibrillator implantation can significantly affect the reported crash risk, necessitating careful consideration in risk assessment.
Article number five. Association of Body Mass Index with ten-year outcomes in asymptomatic stage a/B heart failure patients: Insights from the CHART-2 study. This study prospectively evaluated 501 asymptomatic stage A heart failure patients and 4767 asymptomatic stage B heart failure patients, with a mean age of 67.6 years, 71.1 percent of whom were male. It examined the association of Body Mass Index with ten-year outcomes in these early stage heart failure patients. The research addressed a gap in understanding the prognostic importance of Body Mass Index in asymptomatic heart failure, a topic where previous studies largely focused on stage C and D heart failure patients.
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đ Keywords
Left Ventricular Ejection Fraction, British Columbia, driving risk, heart failure, magnetic resonance imaging, P. A. C. E. D. Score, prognosis, road exposure, Right Ventricular-Pulmonary Arterial coupling, atrial fibrillation ablation, pulmonary regurgitation, pediatric kidney transplant, Tetralogy of Fallot, implantable cardioverter-defibrillator, Body Mass Index, asymptomatic heart failure, allograft failure, kidney function, clinical predictors, rehospitalization, right ventricular outflow tract obstruction, CHART-2 study, motor vehicle crash, Left Ventricular Systolic Dysfunction.
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