PCOS Raises Long-Term Arrhythmia Risk 01/23/26
Welcome to Cardiology Today â Recorded January 23, 2026. This episode summarizes 5 key cardiology studies on topics like arrhythmia detection and smartwatch. Key takeaway: PCOS Raises Long-Term Arrhythmia Risk.
Article Links:
Article 1: Enhanced Detection and Prompt Diagnosis of Atrial Fibrillation Using Apple Watch: A Randomized Controlled Trial. (Journal of the American College of Cardiology)
Article 2: Electromechanically Optimized Right Ventricular Pacing for Obstructive Hypertrophic Cardiomyopathy: The EMORI-HCM Trial. (Journal of the American College of Cardiology)
Article 3: Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium. (Circulation)
Article 4: Polycystic Ovarian Syndrome and the Long-term Risk of Arrhythmias. (Circulation)
Article 5: Sex and gender differences in coronary pathophysiology and ischaemic heart disease. (European heart journal)
Full episode page: https://podcast.explainheart.com/podcast/pcos-raises-long-term-arrhythmia-risk-01-23-26/
đ Featured Articles
Article 1: Enhanced Detection and Prompt Diagnosis of Atrial Fibrillation Using Apple Watch: A Randomized Controlled Trial.
Journal: Journal of the American College of Cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41569211
Summary: Atrial fibrillation, a common cardiac arrhythmia, frequently remains undiagnosed due to its paroxysmal and asymptomatic nature, serving as a major cause of stroke. Wearable technology functions as a scalable, noninvasive screening tool for conditions like atrial fibrillation. A multicenter randomized controlled trial investigated the detection of new onset atrial fibrillation using remote smartwatch-based screening among patients sixty-five years or older with elevated stroke risk. This approach offers a significant pathway for prompt diagnosis, which is crucial for reducing stroke incidence in susceptible populations.
Article 2: Electromechanically Optimized Right Ventricular Pacing for Obstructive Hypertrophic Cardiomyopathy: The EMORI-HCM Trial.
Journal: Journal of the American College of Cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40892619
Summary: Right ventricular pacing in symptomatic obstructive hypertrophic cardiomyopathy, while capable of reducing left ventricular outflow tract gradient, often yields variable net effects due to potential reductions in cardiac output. The E. M. O. R. I. hyphen H. C. M. trial investigated an electromechanically optimized approach for right ventricular pacing. This method involved precise programming of the atrio-ventricular delay to maximize symptomatic benefit. The strategy provides a refined therapeutic option for managing patients with obstructive hypertrophic cardiomyopathy already equipped with pacing devices.
Article 3: Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium.
Journal: Circulation
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41568447
Summary: Long-term outcomes following Fontan palliation exhibit significant variability, despite known predictions of early failure by pre-Fontan hemodynamics. A study from the Pediatric Cardiac Care Consortium investigated the association of pre-Fontan hemodynamics with long-term risks of death or transplantation. The analysis, which utilized data from a U. S. hyphen based multicenter registry, established that specific pre-Fontan hemodynamic parameters are indeed predictive of these critical long-term outcomes. This finding provides valuable insights for risk stratification and prognostic assessment in patients undergoing Fontan procedures.
Article 4: Polycystic Ovarian Syndrome and the Long-term Risk of Arrhythmias.
Journal: Circulation
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41568438
Summary: Polycystic ovarian syndrome is linked to increased cardiovascular morbidity, atherosclerotic cardiovascular disease, and specific electrocardiographic alterations. This study investigated the previously under-researched long-term risk of cardiac arrhythmias in women with polycystic ovarian syndrome. Researchers found a clear association between polycystic ovarian syndrome and an elevated long-term risk of various cardiac arrhythmias. This finding underscores the importance of cardiovascular surveillance in women diagnosed with polycystic ovarian syndrome.
Article 5: Sex and gender differences in coronary pathophysiology and ischaemic heart disease.
Journal: European heart journal
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41571335
Summary: Ischemic heart disease exhibits significant sex and gender differences, necessitating a comprehensive understanding of these dissimilarities for improved patient outcomes. This Scientific Statement reviewed current knowledge, identifying unequal impacts of traditional risk factors between men and women. The review integrated additional contributing factors, including hormonal changes, specific medical treatments for transgender people and cancer patients, and pregnancy-related conditions. This provides a critical framework for understanding diverse coronary pathophysiology and tailoring care in ischemic heart disease across sexes and genders.
đ Transcript
Today’s date is January 23, 2026. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Enhanced Detection and Prompt Diagnosis of Atrial Fibrillation Using Apple Watch: A Randomized Controlled Trial. Atrial fibrillation, a common cardiac arrhythmia, frequently remains undiagnosed due to its paroxysmal and asymptomatic nature, serving as a major cause of stroke. Wearable technology functions as a scalable, noninvasive screening tool for conditions like atrial fibrillation. A multicenter randomized controlled trial investigated the detection of new onset atrial fibrillation using remote smartwatch-based screening among patients sixty-five years or older with elevated stroke risk. This approach offers a significant pathway for prompt diagnosis, which is crucial for reducing stroke incidence in susceptible populations.
Article number two. Electromechanically Optimized Right Ventricular Pacing for Obstructive Hypertrophic Cardiomyopathy: The EMORI-HCM Trial. Right ventricular pacing in symptomatic obstructive hypertrophic cardiomyopathy, while capable of reducing left ventricular outflow tract gradient, often yields variable net effects due to potential reductions in cardiac output. The E. M. O. R. I. hyphen H. C. M. trial investigated an electromechanically optimized approach for right ventricular pacing. This method involved precise programming of the atrio-ventricular delay to maximize symptomatic benefit. The strategy provides a refined therapeutic option for managing patients with obstructive hypertrophic cardiomyopathy already equipped with pacing devices.
Article number three. Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium. Long-term outcomes following Fontan palliation exhibit significant variability, despite known predictions of early failure by pre-Fontan hemodynamics. A study from the Pediatric Cardiac Care Consortium investigated the association of pre-Fontan hemodynamics with long-term risks of death or transplantation. The analysis, which utilized data from a U. S. hyphen based multicenter registry, established that specific pre-Fontan hemodynamic parameters are indeed predictive of these critical long-term outcomes. This finding provides valuable insights for risk stratification and prognostic assessment in patients undergoing Fontan procedures.
Article number four. Polycystic Ovarian Syndrome and the Long-term Risk of Arrhythmias. Polycystic ovarian syndrome is linked to increased cardiovascular morbidity, atherosclerotic cardiovascular disease, and specific electrocardiographic alterations. This study investigated the previously under-researched long-term risk of cardiac arrhythmias in women with polycystic ovarian syndrome. Researchers found a clear association between polycystic ovarian syndrome and an elevated long-term risk of various cardiac arrhythmias. This finding underscores the importance of cardiovascular surveillance in women diagnosed with polycystic ovarian syndrome.
Article number five. Sex and gender differences in coronary pathophysiology and ischaemic heart disease. Ischemic heart disease exhibits significant sex and gender differences, necessitating a comprehensive understanding of these dissimilarities for improved patient outcomes. This Scientific Statement reviewed current knowledge, identifying unequal impacts of traditional risk factors between men and women. The review integrated additional contributing factors, including hormonal changes, specific medical treatments for transgender people and cancer patients, and pregnancy-related conditions. This provides a critical framework for understanding diverse coronary pathophysiology and tailoring care in ischemic heart disease across sexes and genders.
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đ Keywords
arrhythmia detection, smartwatch, pacing optimization, gender differences, cardiac output, death or transplantation, pre-Fontan hemodynamics, wearables, Fontan palliation, sex differences, pediatric cardiology, long-term outcomes, atrial fibrillation, hormonal changes, electrocardiographic alterations, right ventricular pacing, ischemic heart disease, risk factors, obstructive hypertrophic cardiomyopathy, stroke risk, atrio-ventricular delay, arrhythmias, long-term risk, polycystic ovarian syndrome, coronary pathophysiology, cardiovascular morbidity.
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Concise summaries of cardiovascular research for professionals.
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