AI Links Dental Care to Higher Heart Risk 02/23/26
Welcome to Cardiology Today – Recorded February 23, 2026. This episode summarizes 5 key cardiology studies on topics like electrocardiography and adverse outcomes. Key takeaway: AI Links Dental Care to Higher Heart Risk.
Article Links:
Article 1: Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/SIRT1 Axis. (Journal of the American Heart Association)
Article 2: Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea. (Journal of the American Heart Association)
Article 3: Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study. (Journal of the American Heart Association)
Article 4: Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China. (Journal of the American Heart Association)
Article 5: Inadequate Preventive Dental Care Is Associated With Higher Cardiovascular Risk Identified by ECG-Based Artificial Intelligence Algorithms. (Journal of the American Heart Association)
Full episode page: https://podcast.explainheart.com/podcast/ai-links-dental-care-to-higher-heart-risk-02-23-26/
📚 Featured Articles
Article 1: Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/SIRT1 Axis.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717953
Summary: This study found that interferon-gamma-responsive microglia-derived extracellular vesicles inhibited neurogenesis after stroke. This inhibition occurred via the microRNA-199a-5p/SIRT1 axis, revealing a specific molecular mechanism. The data demonstrated a pathway contributing to impaired neurological function recovery following cerebral ischemia. This new understanding identifies a potential therapeutic target to enhance neurogenesis and improve patient outcomes after stroke.
Article 2: Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717952
Summary: This study evaluated annual trends in the control of major risk factors at the time of ischemic stroke in South Korea from 2011 to 2022. Researchers analyzed data from a nationwide registry, focusing on hypertension, diabetes, and dyslipidemia. The findings from this real-world assessment identified specific areas where current prevention guidelines for ischemic stroke need greater clinical attention. This work helps improve early stroke outcomes by highlighting gaps in risk factor management.
Article 3: Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717950
Summary: This study found that short-term exposure to ambient ozone and fine particulate matter with a diameter of less than or equal to 2.5 micrometers increased the risk of in-hospital adverse outcomes for patients with acute myocardial infarction. The time-stratified case-crossover study, conducted in Beijing, demonstrated this association between air pollutants and patient morbidity. This data highlights the critical impact of environmental factors on immediate post-infarction prognosis. Clinicians should consider air quality in managing acute myocardial infarction patients.
Article 4: Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717949
Summary: This large multiregional study in China found that cold waves and geographic elevation strengthened the association of particulate matter exposure with hypertension prevalence. Researchers analyzed data from 27000 adults, demonstrating that these co-occurring environmental stressors exacerbate the known risk of air pollution for hypertension. The data revealed significant interactive effects between long-term particulate matter exposure, cold weather, and altitude. This understanding is crucial for public health strategies addressing hypertension in varied geographical and climatic conditions.
Article 5: Inadequate Preventive Dental Care Is Associated With Higher Cardiovascular Risk Identified by ECG-Based Artificial Intelligence Algorithms.
Journal: Journal of the American Heart Association
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41717947
Summary: This study found that inadequate preventive dental care was associated with a higher cardiovascular risk. Artificial intelligence-enabled electrocardiography algorithms identified this increased risk across several conditions, including atrial fibrillation, aortic stenosis, low ejection fraction, cardiac amyloid, cardiovascular aging, and all-cause mortality. The data demonstrated a clear link between dental health neglect and quantifiable cardiac health markers. These findings underscore the importance of integrating oral health into comprehensive cardiovascular risk assessment and prevention strategies.
📝 Transcript
Today’s date is February 23, 2026. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/SIRT1 Axis. This study found that interferon-gamma-responsive microglia-derived extracellular vesicles inhibited neurogenesis after stroke. This inhibition occurred via the microRNA-199a-5p/SIRT1 axis, revealing a specific molecular mechanism. The data demonstrated a pathway contributing to impaired neurological function recovery following cerebral ischemia. This new understanding identifies a potential therapeutic target to enhance neurogenesis and improve patient outcomes after stroke.
Article number two. Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea. This study evaluated annual trends in the control of major risk factors at the time of ischemic stroke in South Korea from 2011 to 2022. Researchers analyzed data from a nationwide registry, focusing on hypertension, diabetes, and dyslipidemia. The findings from this real-world assessment identified specific areas where current prevention guidelines for ischemic stroke need greater clinical attention. This work helps improve early stroke outcomes by highlighting gaps in risk factor management.
Article number three. Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study. This study found that short-term exposure to ambient ozone and fine particulate matter with a diameter of less than or equal to 2.5 micrometers increased the risk of in-hospital adverse outcomes for patients with acute myocardial infarction. The time-stratified case-crossover study, conducted in Beijing, demonstrated this association between air pollutants and patient morbidity. This data highlights the critical impact of environmental factors on immediate post-infarction prognosis. Clinicians should consider air quality in managing acute myocardial infarction patients.
Article number four. Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China. This large multiregional study in China found that cold waves and geographic elevation strengthened the association of particulate matter exposure with hypertension prevalence. Researchers analyzed data from 27000 adults, demonstrating that these co-occurring environmental stressors exacerbate the known risk of air pollution for hypertension. The data revealed significant interactive effects between long-term particulate matter exposure, cold weather, and altitude. This understanding is crucial for public health strategies addressing hypertension in varied geographical and climatic conditions.
Article number five. Inadequate Preventive Dental Care Is Associated With Higher Cardiovascular Risk Identified by ECG-Based Artificial Intelligence Algorithms. This study found that inadequate preventive dental care was associated with a higher cardiovascular risk. Artificial intelligence-enabled electrocardiography algorithms identified this increased risk across several conditions, including atrial fibrillation, aortic stenosis, low ejection fraction, cardiac amyloid, cardiovascular aging, and all-cause mortality. The data demonstrated a clear link between dental health neglect and quantifiable cardiac health markers. These findings underscore the importance of integrating oral health into comprehensive cardiovascular risk assessment and prevention strategies.
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🔍 Keywords
electrocardiography, adverse outcomes, fine particulate matter, stroke, ischemic stroke, particulate matter, cardiovascular risk, hypertension, artificial intelligence, neurogenesis, dyslipidemia, atrial fibrillation, extracellular vesicles, air pollution, cold waves, microglia, risk factor control, acute myocardial infarction, geographic elevation, diabetes, ozone, dental care, SIRT1.
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Concise summaries of cardiovascular research for professionals.
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