CVD Causes 26.5% Maternal Deaths in Pregnancy 01/19/26
Welcome to Cardiology Today â Recorded January 19, 2026. This episode summarizes 5 key cardiology studies on topics like patient suitability and transcatheter tricuspid valve replacement. Key takeaway: CVD Causes 26.5% Maternal Deaths in Pregnancy.
Article Links:
Article 1: Trends, variation, and predictors of coronary angiography in potential cardiac organ donors. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
Article 2: Pregnancy Outcomes in Women with Cardiovascular Disease: A Retrospective Cohort Study from Kaiser Permanente Northern California. (The American journal of cardiology)
Article 3: Real-World Suitability of Patients for Transcatheter Tricuspid Valve Replacement. (The American journal of cardiology)
Article 4: Impact Of Comprehensive STEMI Protocol On Process Metrics And Clinical Outcomes In STEMI Patients With Non-System Delay. (The American journal of cardiology)
Full episode page: https://podcast.explainheart.com/podcast/cvd-causes-26-5-maternal-deaths-in-pregnancy-01-19-26/
đ Featured Articles
Article 1: Trends, variation, and predictors of coronary angiography in potential cardiac organ donors.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41548728
Summary: Invasive coronary angiography for screening coronary artery disease in younger potential heart donors is discretionary, leading to variation in practice. This study characterized the patterns and influencing factors of invasive coronary angiography use in brain-dead potential heart donors in the United States between 2018 and 2023. The findings clarified existing variability in screening practices for coronary artery disease in this vital population. These insights are essential for establishing standardized protocols and improving the selection process for donor hearts in transplantation.
Article 2: Pregnancy Outcomes in Women with Cardiovascular Disease: A Retrospective Cohort Study from Kaiser Permanente Northern California.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41548861
Summary: Cardiovascular disease accounts for 26.5 percent of pregnancy-related deaths, highlighting its significant impact on maternal mortality. This retrospective cohort study characterized maternal, obstetric, and fetal outcomes among pregnant women with pre-existing cardiovascular disease. The study included patients with conditions such as moderate or greater valvular heart disease, cardiomyopathy, and congenital heart disease. These findings are crucial for optimizing management and improving safety for high-risk pregnant individuals.
Article 3: Real-World Suitability of Patients for Transcatheter Tricuspid Valve Replacement.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41548860
Summary: Transcatheter tricuspid valve replacement demonstrates therapeutic promise for severe tricuspid regurgitation, yet many patients face ineligibility due to anatomic limitations. This study identified patients referred for transcatheter tricuspid valve intervention who were subsequently deemed ineligible for transcatheter tricuspid valve replacement. Analyzing 251 patients, the study clarified the real-world challenges of patient selection and the implications for those unable to undergo replacement due to anatomical barriers. These findings underscore the practical applicability and patient suitability for advanced tricuspid valve therapies.
Article 4: Impact Of Comprehensive STEMI Protocol On Process Metrics And Clinical Outcomes In STEMI Patients With Non-System Delay.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41548858
Summary: A four-step comprehensive S. T. elevation myocardial infarction protocol improved process metrics and clinical outcomes for S. T. elevation myocardial infarction patients experiencing non-system delays. The observational cohort analysis demonstrated benefits in patients with factors like difficult vascular access, which commonly cause delays to primary percutaneous coronary intervention. This protocol enhances the management of high-risk S. T. elevation myocardial infarction patients who often face suboptimal outcomes due to inherent logistical challenges.
Article 5: Study design of the Akershus Cardiac Examination (ACE) 4 Study: Pragmatic randomized-controlled trial assessing the effect of early biomarker measurements and structured feedback in unselected patients hospitalized with tachypnea.
Journal: Cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41543984
Summary: The Akershus Cardiac Examination 4 Study is a pragmatic randomized-controlled trial designed to evaluate the effect of early biomarker measurements and structured feedback in patients hospitalized with tachypnea. This trial investigates whether early N-terminal pro-B-type natriuretic peptide and cardiac troponin T measurements, coupled with structured electronic health record feedback, improve diagnostic accuracy and risk stratification in the emergency department. The study design targets the diagnostic challenges of acute tachypnea, aiming to optimize biomarker utilization for cardiovascular disease patients.
đ Transcript
Today’s date is January 19, 2026. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Trends, variation, and predictors of coronary angiography in potential cardiac organ donors. Invasive coronary angiography for screening coronary artery disease in younger potential heart donors is discretionary, leading to variation in practice. This study characterized the patterns and influencing factors of invasive coronary angiography use in brain-dead potential heart donors in the United States between 2018 and 2023. The findings clarified existing variability in screening practices for coronary artery disease in this vital population. These insights are essential for establishing standardized protocols and improving the selection process for donor hearts in transplantation.
Article number two. Pregnancy Outcomes in Women with Cardiovascular Disease: A Retrospective Cohort Study from Kaiser Permanente Northern California. Cardiovascular disease accounts for 26.5 percent of pregnancy-related deaths, highlighting its significant impact on maternal mortality. This retrospective cohort study characterized maternal, obstetric, and fetal outcomes among pregnant women with pre-existing cardiovascular disease. The study included patients with conditions such as moderate or greater valvular heart disease, cardiomyopathy, and congenital heart disease. These findings are crucial for optimizing management and improving safety for high-risk pregnant individuals.
Article number three. Real-World Suitability of Patients for Transcatheter Tricuspid Valve Replacement. Transcatheter tricuspid valve replacement demonstrates therapeutic promise for severe tricuspid regurgitation, yet many patients face ineligibility due to anatomic limitations. This study identified patients referred for transcatheter tricuspid valve intervention who were subsequently deemed ineligible for transcatheter tricuspid valve replacement. Analyzing 251 patients, the study clarified the real-world challenges of patient selection and the implications for those unable to undergo replacement due to anatomical barriers. These findings underscore the practical applicability and patient suitability for advanced tricuspid valve therapies.
Article number four. Impact Of Comprehensive STEMI Protocol On Process Metrics And Clinical Outcomes In STEMI Patients With Non-System Delay. A four-step comprehensive S. T. elevation myocardial infarction protocol improved process metrics and clinical outcomes for S. T. elevation myocardial infarction patients experiencing non-system delays. The observational cohort analysis demonstrated benefits in patients with factors like difficult vascular access, which commonly cause delays to primary percutaneous coronary intervention. This protocol enhances the management of high-risk S. T. elevation myocardial infarction patients who often face suboptimal outcomes due to inherent logistical challenges.
Article number five. Study design of the Akershus Cardiac Examination (ACE) 4 Study: Pragmatic randomized-controlled trial assessing the effect of early biomarker measurements and structured feedback in unselected patients hospitalized with tachypnea. The Akershus Cardiac Examination 4 Study is a pragmatic randomized-controlled trial designed to evaluate the effect of early biomarker measurements and structured feedback in patients hospitalized with tachypnea. This trial investigates whether early N-terminal pro-B-type natriuretic peptide and cardiac troponin T measurements, coupled with structured electronic health record feedback, improve diagnostic accuracy and risk stratification in the emergency department. The study design targets the diagnostic challenges of acute tachypnea, aiming to optimize biomarker utilization for cardiovascular disease patients.
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đ Keywords
patient suitability, transcatheter tricuspid valve replacement, transcatheter tricuspid valve intervention, anatomic limitations, transplant recipients, cardiovascular disease, risk stratification, congenital heart disease, coronary artery disease, clinical outcomes, coronary angiography, valvular heart disease, heart donors, non-system delays, tachypnea, S. T. elevation myocardial infarction, pregnancy outcomes, tricuspid regurgitation, diagnostic accuracy, donor selection, comprehensive S. T. elevation myocardial infarction protocol, cardiomyopathy, emergency department, cardiac troponin T, maternal mortality, N-terminal pro-B-type natriuretic peptide, primary percutaneous coronary intervention.
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Concise summaries of cardiovascular research for professionals.
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